In contrast, it would be appropriate to discourage use of products when there is strong evidence for lack of quality, safety, or efficacy. No supplements discussed in this review meet these criteria, however. If there is strong evidence for a product’s quality, safety, and efficacy, it may be reasonable to recommend that product and closely monitor the patient. John’s wort in weight loss, physicians should caution patients about the use of these supplements and closely monitor those who choose to use these products.Ĭriteria adapted from a recent review 45 can be used to develop clinical recommendations for each supplement. Because of insufficient or conflicting evidence regarding the efficacy of conjugated linoleic acid, ginseng, glucomannan, green tea, hydroxycitric acid,l-carnitine, psyllium, pyruvate, and St. Guar gum and chitosan appear to be ineffective therefore, use of these products should be discouraged. Chromium is a popular weight-loss supplement, but its efficacy and long-term safety are uncertain. Food and Drug Administration to ban the sale of these products. Although evidence of modest weight loss secondary to ephedra-caffeine ingestion exists, potentially serious adverse effects have led the U.S. Currently, no weight-loss supplements meet criteria for recommended use. More than 50 individual dietary supplements and more than 125 commercial combination products are available for weight loss. A schema for whether physicians should recommend, caution, or discourage use of a particular weight-loss supplement is presented in this article. Asking overweight patients about their use of weight-loss supplements and understanding the evidence for the efficacy, safety, and quality of these supplements are critical when counseling patients regarding weight loss. Over-the-counter dietary supplements to treat obesity appeal to many patients who desire a “magic bullet” for weight loss.
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